Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FES | P07332 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | MARK3 | P27448 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960109 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAHTTL3MBTL1 | |
| SCHEMBL2698425 | 0.80 | USP2 (0.70) | RECQLUSP2ALDH1A1MAPTLMNA | |
| SCHEMBL7868094 | 0.78 | TP53 (0.57) | ALDH1A1LMNAHTTKMT2APKM | |
| SCHEMBL4747913 | 0.77 | RECQL (0.62) | RECQLUSP2ALDH1A1MAPTLMNA | |
| SCHEMBL29550751 | 0.77 | RECQL (1.00) | RECQLUSP2ALDH1A1MAPTLMNA | |
| SCHEMBL163993 | 0.77 | RECQL (1.00) | RECQLUSP2ALDH1A1MAPTLMNA | |
| SCHEMBL10157136 | 0.76 | USP2 (0.65) | RECQLUSP2ALDH1A1MAPTLMNA | |
| SCHEMBL774098 | 0.76 | USP2 (0.68) | RECQLUSP2ALDH1A1MAPTLMNA | |
| SCHEMBL7756436 | 0.76 | RECQL (0.64) | RECQLUSP2ALDH1A1MAPTLMNA | |
| SCHEMBL31321074 | 0.76 | USP2 (0.68) | RECQLUSP2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172064-B1 | METALLOPROTEASE INHIBITOR; ANTIARTHRITIC AGENTS, ANTIDIABETIC AGENTS; ANTITUMOR AGENTS | GLAXO WELLCOME INC. | 2001-01-09 | — | — | US | disclosed |