SCHEMBL7960565

SCHEMBL7960565

CC(N)C[Si](C)(C)c1ccccc1[Si](C)(C)CCCN

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.32
SLC6A2 P23975 2/20 0.32
TAAR1 Q96RJ0 2/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CYP2A6 P11509 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
HTR2A P28223 1/20 0.32
HRH1 P35367 1/20 0.32
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003572 0.86 MAOA (0.37) MAOATAAR1CYP2A6HTR2AHRH1
SCHEMBL7960568 0.79 NR1H2 (0.35)
SCHEMBL8625948 0.69
SCHEMBL3865502 0.69 MGAM (0.40) MAOATAAR1CYP2A6HTR2AHRH1
SCHEMBL486510 0.65 NR1H2 (0.43) MAOAHRH1
SCHEMBL7955809 0.63 NR1H2 (0.32) MAOATAAR1
SCHEMBL8141356 0.62
SCHEMBL10611414 0.61 MAOA (0.40) MAOATAAR1CYP2A6HTR2AHRH1
SCHEMBL3919950 0.60 NR1H2 (0.42) MAOAHRH1
SCHEMBL19600567 0.60 TAAR1 (0.47) SLC6A2TAAR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6274754-B1 HYDROSILYLATION; N,N-BIS(TRIMETHYLSILYL)ALLYLAMINE AND BIS(DIMETHYLSILYL)BENZENE IN PRESENCE OF PLATINUM CATALYST SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-14 US disclosed