Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554859 | 0.83 | CYP3A4 (0.55) | CYP3A4TSHRTDP1JAK3MKNK1 | |
| SCHEMBL2087642 | 0.73 | BACE1 (0.42) | MEN1KMT2AMAPTMAPK1RECQL | |
| SCHEMBL7961759 | 0.73 | TTR (0.44) | CYP3A4TSHRMEN1KMT2AMAPT | |
| SCHEMBL8439142 | 0.69 | TSHR (0.50) | CYP3A4TSHRTDP1JAK3MKNK1 | |
| SCHEMBL11632846 | 0.67 | NQO2 (0.38) | CYP3A4TSHRTDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11750655 | 0.65 | NQO2 (0.36) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL23643511 | 0.64 | NFKB1 (0.52) | CYP3A4TSHRMEN1KMT2AMAPT | |
| SCHEMBL13759771 | 0.64 | ARG1 (0.44) | MEN1KMT2AMAPTMAPK1CA1 | |
| SCHEMBL12895790 | 0.64 | MAPT (0.41) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL25495161 | 0.64 | MAPT (0.49) | MEN1KMT2AMAPTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262053-B1 | EFFECTIVE FOR TREATING TUMOR CELLS AND PARTICULARLY EFFECTIVE TO INDUCE APOPTOSIS IN LEUKEMIA AND BREAST TUMOR CELLS. | PARKER HUGHES INSTITUTE | 2001-07-17 | — | — | US | claimed |