Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960772 | 0.83 | CYP3A4 (0.44) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL8439142 | 0.78 | TSHR (0.50) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL1686630 | 0.75 | APEX1 (0.50) | TDP1CA1CA2CA4CA6 | |
| SCHEMBL18224 | 0.71 | CYP3A4 (1.00) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL69980 | 0.71 | CYP3A4 (0.65) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL581997 | 0.71 | CRHBP (0.70) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL3115237 | 0.71 | LMNA (0.59) | CYP3A4TSHRTDP1MEN1KMT2A | |
| Phosphonic Acid SCHEMBL5935327 | 0.69 | TSHR (0.41) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL11020186 | 0.69 | CYP3A4 (0.93) | CYP3A4TSHRTDP1MEN1KMT2A | |
| SCHEMBL4340169 | 0.69 | CYP3A4 (0.93) | CYP3A4TSHRTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312290-B2 | Curable formulations, cured compositions, and articles derived thereform | GENERAL ELECTRIC COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| US-4866155-A | HEAT, RADIATION RESISTANCE; TRANSPARENCY | HOECHST CELANESE CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |
| EP-0323561-A2 | Polyesters of bis (2-(4-hydroxyphenyl) hexafluoroisopropyl)- diphenyl ether | HOECHST CELANESE CORPORATION (US) | 1989-07-12 | — | — | EP | disclosed |
| US-4444960-A | POLYESTER, POLYSULFONATE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-04-24 | — | — | US | disclosed |
| US-4284549-A | COMPRISING A POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A BISPHENOL AN POLYPHENYLENE SULFIDE | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-08-18 | — | — | US | disclosed |
| US-4256625-A | PERFLUOROALKENYLOXY, N-PHOSPHATOALKYL-SULFAMOYL-BENZENE SURFACTANT | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-03-17 | — | — | US | disclosed |
| US-4251429-A | COMPRISING POLYPHENYLENE SULFIDE AND AN AROMATIC POLYESTER | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4211687-A | AROMATIC POLYESTER, POLYPHENYLENE SULFIDE, HALO DIELS-ADER ADDUCT | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-07-08 | — | — | US | disclosed |
| US-4187259-A | Polymer blends with improved hydrolytic stability comprising a linear aromatic polyester and a methacrylate cross-linked acrylate copolymer | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-02-05 | — | — | US | disclosed |
| EP-0007171-A1 | Polymer compositions, molded articles and films with improved hydrolytic stability | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-01-23 | — | — | EP | disclosed |
| US-4137278-A | TRANSESTERIFICATION CATALYST | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1979-01-30 | — | — | US | disclosed |
| US-4126602-A | THERMOPLASTIC, MOLDING, HYDROLYTIC STABILITY | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4079034-A | AROMATIC POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A HALOGENATED BISPHENOL | HOOKER CHEMICALS & PLASTICS CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |