Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL5935327 | 0.89 | TSHR (0.41) | TSHRCYP3A4TDP1HSD17B10ALDH1A1 | |
| SCHEMBL10554859 | 0.78 | CYP3A4 (0.55) | TSHRCYP3A4TDP1HSD17B10ALDH1A1 | |
| SCHEMBL13145946 | 0.73 | ALOX15 (0.50) | CYP3A4HSD17B10ALDH1A1HIF1AALOX15 | |
| SCHEMBL5511479 | 0.72 | SELL (0.48) | TSHRCYP3A4TDP1HSD17B10ALDH1A1 | |
| Propane SCHEMBL28284698 | 0.72 | TSHR (0.42) | TSHRCYP3A4TDP1HSD17B10ALDH1A1 | |
| SCHEMBL3115237 | 0.72 | LMNA (0.59) | TSHRCYP3A4TDP1HSD17B10ALDH1A1 | |
| SCHEMBL26940683 | 0.70 | CA1 (0.52) | CYP3A4HSD17B10ALDH1A1HIF1AALOX15 | |
| SCHEMBL8435639 | 0.70 | TTR (0.52) | TSHRCYP3A4HSD17B10ALDH1A1HIF1A | |
| SCHEMBL10965241 | 0.70 | ALDH1A1 (0.34) | TSHRCYP3A4HSD17B10ALDH1A1HIF1A | |
| SCHEMBL2258347 | 0.70 | CA2 (0.48) | TSHRHSD17B10ALOX15ALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858695-A | SUBJECTING BILIRUBIN TO COEXIST WITH ASCORBATE OXIDASE AND A REACTION PROMOTER IN AQUEOUS MEDIUM TO THEREBY OXIDIZE THE BILIRUBIN, MEASURING THE CHANGE IN ABSORBANCE | KYOWA MEDEX CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0770688-A1 | Method of quantitative determination of bilirubin and a reagent therefor | KYOWA MEDEX CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |