Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964338 | 0.90 | CYP11B2 (0.35) | KCNMA1CHRNB4CHRNA3 | |
| SCHEMBL7963738 | 0.84 | KCNMA1 (0.37) | DPP4KCNMA1 | |
| SCHEMBL2157391 | 0.82 | CYP11B2 (0.40) | USP30CHRNB4CHRNA3 | |
| SCHEMBL7965050 | 0.80 | CYP2C19 (0.33) | DPP4 | |
| SCHEMBL8326401 | 0.80 | DHODH (0.37) | — | |
| SCHEMBL7961198 | 0.80 | MEN1 (0.34) | — | |
| SCHEMBL7962835 | 0.80 | ALDH1A1 (0.33) | DPP4CD274 | |
| SCHEMBL7961349 | 0.78 | KCNMA1 (0.34) | DPP4KCNMA1CD274USP30CHRNB4 | |
| SCHEMBL7961452 | 0.76 | KCNMA1 (0.38) | DPP4KCNMA1 | |
| SCHEMBL7967718 | 0.76 | KCNMA1 (0.36) | DPP4KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |