Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959589 | 0.90 | PPARA (0.56) | L3MBTL1FFAR1LMNAPPARAPLA2G4B | |
| SCHEMBL2468006 | 0.82 | L3MBTL1 (0.69) | L3MBTL1MMP2FFAR1LMNATSHR | |
| SCHEMBL38674 | 0.81 | L3MBTL1 (0.68) | L3MBTL1MMP2FFAR1LMNATSHR | |
| SCHEMBL19043148 | 0.80 | L3MBTL1 (0.72) | L3MBTL1MMP2FFAR1LMNAMCL1 | |
| SCHEMBL1806524 | 0.80 | L3MBTL1 (1.00) | L3MBTL1MMP2FFAR1LMNATSHR | |
| SCHEMBL11682151 | 0.80 | L3MBTL1 (0.67) | L3MBTL1MMP2FFAR1LMNATSHR | |
| SCHEMBL12117110 | 0.80 | L3MBTL1 (0.67) | L3MBTL1MMP2FFAR1LMNATSHR | |
| SCHEMBL652824 | 0.80 | L3MBTL1 (0.67) | L3MBTL1MMP2FFAR1LMNATSHR | |
| SCHEMBL2234098 | 0.80 | PKM (0.69) | L3MBTL1MMP2TSHRPPARAPLA2G4B | |
| SCHEMBL7046292 | 0.80 | L3MBTL1 (0.67) | L3MBTL1MMP2FFAR1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |