Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1545776 | 0.74 | CYP1A2 (0.41) | MKNK1MKNK2MAPK13RAF1MAPK9 | |
| Hydrochloric Acid SCHEMBL6221807 | 0.73 | CYP1A2 (0.41) | MKNK1MKNK2MAPK13RAF1MAPK9 | |
| SCHEMBL6220554 | 0.71 | HTR1A (0.40) | — | |
| SCHEMBL7954724 | 0.71 | MKNK1 (0.40) | MKNK1MKNK2MAPK13RAF1MAPK9 | |
| SCHEMBL7955068 | 0.69 | GRM4 (0.40) | — | |
| SCHEMBL7966598 | 0.66 | HTR2C (0.46) | CHRM4 | |
| SCHEMBL1545124 | 0.64 | KDM4E (0.49) | — | |
| Hydrochloric Acid SCHEMBL1838069 | 0.63 | KDM4E (0.51) | — | |
| SCHEMBL7964862 | 0.61 | JUND (0.39) | — | |
| SCHEMBL19262502 | 0.61 | SLC6A2 (0.42) | MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207680-B1 | FOR THERAPY OF PSYCHOLOGICAL DISORDERS AND PAIN | AVENTIS PHARMACEUTICALS INC. | 2001-03-27 | — | — | US | disclosed |