Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.32 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405031 | 0.85 | MAP3K7 (0.44) | APPMAP3K7TAB1LMNAKCNN4 | |
| SCHEMBL7974226 | 0.83 | KDM4E (0.44) | NR4A2MAP3K7TAB1LMNANPC1 | |
| SCHEMBL18065068 | 0.79 | TRPM8 (0.36) | TRPM8KCNN4 | |
| SCHEMBL8490705 | 0.73 | TRPA1 (0.38) | LMNAALOX5NPC1 | |
| SCHEMBL7978927 | 0.73 | AKR1C3 (0.42) | NR4A2 | |
| SCHEMBL8487037 | 0.72 | — | — | |
| SCHEMBL7962818 | 0.71 | EPHX2 (0.38) | APPEPHX2 | |
| SCHEMBL6821626 | 0.70 | RECQL (0.50) | LMNANPC1 | |
| SCHEMBL1830315 | 0.70 | KCNN4 (0.40) | NR4A2LMNAKCNN4NPC1KDM4E | |
| SCHEMBL7789115 | 0.69 | SIRT2 (0.42) | APPEPHX2NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081317-A1 | CHIRAL IMIDAZOYL INTERMEDIATES FOR THE SYNTHESIS OF 2-(4-IMIDAZOYL)-CYCLOPROPYL DERIVATIVES | GLIATECH, INC. (US) | 2001-11-01 | — | — | WO | disclosed |