Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 14/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 3/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342642 | 0.78 | GAA (0.63) | NAAA | |
| SCHEMBL6177700 | 0.78 | NAAA (0.67) | NAAACTSLASAH1RIPK1 | |
| SCHEMBL4079431 | 0.76 | NAAA (0.85) | NAAACTSLASAH1 | |
| SCHEMBL4073924 | 0.76 | NAAA (0.85) | NAAACTSLASAH1 | |
| SCHEMBL4073930 | 0.76 | NAAA (0.85) | NAAACTSLASAH1 | |
| SCHEMBL6181701 | 0.76 | ALDH1A1 (0.44) | NAAACTSLASAH1 | |
| SCHEMBL6178886 | 0.76 | CTSK (0.43) | NAAACTSL | |
| SCHEMBL644741 | 0.75 | SCN9A (0.47) | NAAACTSLRIPK1 | |
| SCHEMBL6176791 | 0.74 | NAAA (0.48) | NAAACTSL | |
| SCHEMBL13140087 | 0.74 | RIPK1 (0.42) | NAAACTSLRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239131-B1 | WHICH HAVE GASTRIN AND/OR CCK-B (CHOLECYSTOKININ-B) RECEPTOR ANTAGONISM, USEFUL AS REMEDIES FOR GASTRIC ULCER AND GASTROINTESTINAL MOVEMENT DISORDER. | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-29 | — | — | US | disclosed |