SCHEMBL7963317

SCHEMBL7963317

Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc3c(c2NC(=O)c2ccc4ccccc4c2)NC(=O)CO3)c1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.34
NPC1 O15118 3/20 0.34
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
PLD2 O14939 3/20 0.33
PLD1 Q13393 3/20 0.33
KMT2A Q03164 3/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ROCK2 O75116 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
MEN1 O00255 2/20 0.32
TP53 P04637 1/20 0.32
MCL1 Q07820 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7967434 0.82 ALDH1A1 (0.39) RAB9ANPC1ALDH1A1POLBMAPT
SCHEMBL7565226 0.77 NPC1 (0.38) RAB9ANPC1ALDH1A1TP53SMN1; SMN2
SCHEMBL6849141 0.76
SCHEMBL7563867 0.67 NR3C2 (0.39) POLBMAPTTP53
SCHEMBL7977920 0.65 NR3C2 (0.45)
SCHEMBL7955280 0.64 RAB9A (0.38) RAB9ANPC1POLBMAPTKMT2A
SCHEMBL7965406 0.63
SCHEMBL9222926 0.60 PTGES (0.31)
SCHEMBL7706993 0.60 PTGES (0.37) ALDH1A1MAPTKMT2AMEN1
SCHEMBL6800796 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294503-B1 HERBICIDAL COMPOSITIONS CONTAINING HETEROCYCLES ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-09-25 US claimed
US-6294503-B1 HERBICIDAL COMPOSITIONS CONTAINING HETEROCYCLES ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-09-25 US disclosed