SCHEMBL7565226

SCHEMBL7565226

COc1c(Cl)cc(F)c(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c1NC(=O)c1ccc2ccccc2c1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
CASP3 P42574 2/20 0.38
SENP7 Q9BQF6 2/20 0.38
GAA P10253 2/20 0.38
ALDH1A1 P00352 1/20 0.38
NQO2 P16083 1/20 0.37
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TLR7 Q9NYK1 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
TAS1R2 Q8TE23 1/20 0.36
KCNJ11 Q14654 3/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
PLAU P00749 1/20 0.35
PTPN1 P18031 1/20 0.35
PTGES O14684 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636705 0.83 PTGES (0.33) NPC1RAB9AGAAALDH1A1LMNA
SCHEMBL7706993 0.82 PTGES (0.37) ALDH1A1LMNAPTGES
SCHEMBL5437243 0.79 KDM4E (0.41) NPC1RAB9ACASP3SENP7TLR7
SCHEMBL5388347 0.78 CASP3 (0.44) NPC1RAB9ACASP3SENP7GAA
SCHEMBL7963317 0.77 RAB9A (0.34) NPC1RAB9AGAAALDH1A1SMN1; SMN2
SCHEMBL7668209 0.71 BCAT2 (0.32)
SCHEMBL7657861 0.71 BCAT2 (0.32)
SCHEMBL7559209 0.70 GRIN2D (0.38)
SCHEMBL8682441 0.70
SCHEMBL8683761 0.69 SMN1; SMN2 (0.34) NPC1RAB9AALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6455469-B1 SUBSTITUTED ACETANILIDE DERIVATIVE IN COMBINATION WITH OTHER HERBICIDE TO GIVE EFFECTIVE WEED CONTORL ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-09-24 US disclosed
US-20020107148-A1 Herbicidal composition ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107148-A1 Herbicidal composition CPS1, HADHB, DDT NPC1 4375/4885RAB9A 4404/4885CASP3 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.