Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 5/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.59 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HRH1 | P35367 | 3/20 | 0.59 |
| ▸ | HTR2B | P41595 | 3/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.59 |
| ▸ | DRD1 | P21728 | 3/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8311562 | 0.98 | DRD3 (0.58) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9182337 | 0.91 | CYP2D6 (0.68) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| SCHEMBL8317437 | 0.90 | DRD3 (0.61) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL28643710 | 0.88 | DRD3 (0.59) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| SCHEMBL7952124 | 0.84 | OPRD1 (0.54) | OPRM1KMT2AOPRD1MEN1ALDH1A1 | |
| SCHEMBL7391541 | 0.83 | ACHE (0.73) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| SCHEMBL8371748 | 0.82 | OPRD1 (0.67) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| SCHEMBL4249388 | 0.82 | LMNA (0.60) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| SCHEMBL8371746 | 0.82 | OPRM1 (0.59) | DRD3CHRM2ADRA2AKCNH2CYP2D6 | |
| SCHEMBL7381083 | 0.82 | DRD3 (0.60) | DRD3CHRM2ADRA2AKCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310067-B1 | 1-(DIPHENYLMETHYL-PIPERAZINYLETHYL)UROCANIC ACID METHYL ESTER FOR EXAMPLE; GOOD SOLUBILITY; TREATING ALLERGIC DISEASES | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1054003-A1 | UROCANIC ACID DERIVATIVES | Senju Pharmaceutical Co., Ltd. (JP) | 2000-11-22 | — | — | EP | disclosed |
| US-4792554-A | Pyridine compounds, pharaceutical compositions, their use in allergy therapy | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-12-20 | — | — | US | disclosed |
| EP-0032058-B1 | THIAZOLE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4411900-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-25 | — | — | US | disclosed |
| EP-0032058-A1 | Thiazole derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |