Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963809 | 1.00 | KDM1A (0.45) | KDM1AMAOAMAOBOPRM1OPRD1 | |
| SCHEMBL7963808 | 1.00 | KDM1A (0.45) | KDM1AMAOAMAOBOPRM1OPRD1 | |
| SCHEMBL7970904 | 0.80 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1TRPV6 | |
| SCHEMBL9999607 | 0.78 | ALDH1A1 (0.44) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL14619610 | 0.78 | ALDH1A1 (0.44) | OPRM1OPRD1OPRK1OPRL1MAPT | |
| SCHEMBL7702059 | 0.77 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1TRPV6 | |
| SCHEMBL7707357 | 0.77 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1TRPV6 | |
| SCHEMBL27814321 | 0.77 | KDM1A (0.51) | KDM1AMAOAMAOBDRD4 | |
| SCHEMBL7967371 | 0.76 | CCRL2 (0.43) | OPRM1OPRD1OPRK1OPRL1DRD4 | |
| Hydrochloric Acid SCHEMBL7971161 | 0.76 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326372-B1 | BENIGN PROSTATE HYPERPLASIA | MERCK & CO., INC. | 2001-12-04 | — | — | US | disclosed |