Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCRL2 | O00421 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 7/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971160 | 0.99 | CCRL2 (0.43) | CCRL2CCR2KCNH2OPRM1OPRD1 | |
| SCHEMBL30131210 | 0.85 | KMT2A (0.47) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL16803154 | 0.85 | KMT2A (0.47) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| Hydrochloric Acid SCHEMBL30562858 | 0.84 | KMT2A (0.46) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL7966071 | 0.81 | DRD4 (0.39) | CCRL2CCR2KCNH2OPRM1OPRD1 | |
| Carbamic Acid SCHEMBL10474895 | 0.80 | ALDH1A1 (0.46) | KMT2APOLBHSD11B1DRD4DRD2 | |
| SCHEMBL7707357 | 0.79 | OPRM1 (0.40) | CCRL2CCR2KCNH2OPRM1OPRD1 | |
| SCHEMBL7702059 | 0.79 | OPRM1 (0.40) | CCRL2CCR2KCNH2OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7971161 | 0.78 | OPRM1 (0.40) | CCRL2CCR2KCNH2OPRM1OPRD1 | |
| SCHEMBL31250321 | 0.77 | KMT2A (0.43) | OPRM1OPRD1OPRK1OPRL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |