Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952967 | 0.90 | DPP4 (0.35) | KCNMA1HCRTR1HCRTR2DPP4ALDH1A1 | |
| SCHEMBL7962855 | 0.89 | HCRTR1 (0.37) | KCNMA1HCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL8329371 | 0.89 | DPP4 (0.35) | KCNMA1HCRTR1HCRTR2DPP4ALDH1A1 | |
| SCHEMBL7964348 | 0.88 | KDM4E (0.35) | KCNMA1DPP4ALDH1A1HPGDMAPT | |
| SCHEMBL7962103 | 0.88 | MEN1 (0.35) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7961108 | 0.87 | DHODH (0.35) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7962570 | 0.86 | CDK5 (0.34) | HCRTR2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7961452 | 0.84 | KCNMA1 (0.38) | KCNMA1DPP4ALDH1A1MAPTKDM4E | |
| SCHEMBL7963301 | 0.83 | HCRTR1 (0.34) | HCRTR1MEN1KMT2AALDH1A1IDO1 | |
| SCHEMBL7961349 | 0.83 | KCNMA1 (0.34) | KCNMA1DPP4ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |