Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 4/20 | 0.30 |
| ▸ | ELANE | P08246 | 3/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329371 | 0.91 | DPP4 (0.35) | KDM4ERECQLDPP4KCNMA1GAA | |
| SCHEMBL7952967 | 0.90 | DPP4 (0.35) | KDM4ERECQLDPP4KCNMA1GAA | |
| SCHEMBL7961440 | 0.88 | KDM4E (0.35) | KDM4ERECQLKCNMA1UCHL1BTK | |
| SCHEMBL7963885 | 0.88 | KCNMA1 (0.36) | KDM4EDPP4KCNMA1GAAHPGD | |
| SCHEMBL7952522 | 0.87 | ALDH1A1 (0.35) | GAAHPGDALDH1A1MAPTRAB9A | |
| SCHEMBL7961452 | 0.87 | KCNMA1 (0.38) | KDM4ERECQLDPP4KCNMA1GAA | |
| SCHEMBL7961792 | 0.85 | DHODH (0.36) | HPGDALDH1A1PDE4B | |
| SCHEMBL7963738 | 0.83 | KCNMA1 (0.37) | DPP4KCNMA1 | |
| SCHEMBL7968397 | 0.82 | FAAH (0.33) | HPGDALDH1A1 | |
| SCHEMBL7961238 | 0.82 | ALDH1A1 (0.32) | HPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |