Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | NSD2 | O96028 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965416 | 0.90 | ABL1 (0.37) | HCRTR1IDO1SCN9AMEN1KMT2A | |
| SCHEMBL7952972 | 0.90 | HCRTR1 (0.34) | HCRTR1NSD2SCN9ACYP2C19POLB | |
| SCHEMBL7961238 | 0.88 | ALDH1A1 (0.32) | HCRTR1NSD2CYP2C19POLBALDH1A1 | |
| SCHEMBL7962103 | 0.88 | MEN1 (0.35) | IDO1CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL7961108 | 0.87 | DHODH (0.35) | HCRTR1IDO1CYP2C19ALDH1A1MEN1 | |
| SCHEMBL7962570 | 0.86 | CDK5 (0.34) | IDO1CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL7963885 | 0.83 | KCNMA1 (0.36) | HCRTR1IDO1ALDH1A1MEN1KMT2A | |
| SCHEMBL7963509 | 0.81 | CFTR (0.40) | HCRTR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7964731 | 0.80 | FPR1 (0.35) | IDO1ALDH1A1MEN1KMT2A | |
| SCHEMBL7965403 | 0.79 | HCRTR1 (0.34) | HCRTR1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |