Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16058225 | 0.81 | LOXL2 (0.58) | LOXL2SMN1; SMN2KMT2A | |
| SCHEMBL30131477 | 0.81 | LOXL2 (0.58) | LOXL2SMN1; SMN2KMT2A | |
| SCHEMBL26786803 | 0.79 | P2RX7 (0.51) | SCN9ASCN10ALOXL2ULK1 | |
| SCHEMBL9017207 | 0.75 | LMNA (0.56) | P2RX3KMT2A | |
| SCHEMBL7963938 | 0.73 | ALDH1A1 (0.42) | SCN9ASCN10AULK1KMT2A | |
| SCHEMBL12678026 | 0.73 | P2RX7 (0.61) | SCN9ASCN10ALOXL2ULK1 | |
| SCHEMBL30469338 | 0.73 | ALDH1A1 (0.60) | SCN9ASCN10ALOXL2ULK1 | |
| SCHEMBL19075361 | 0.70 | KMT2A (0.55) | SMN1; SMN2KMT2A | |
| SCHEMBL12129562 | 0.69 | KDM4E (0.58) | SCN9ASMN1; SMN2 | |
| SCHEMBL27202071 | 0.68 | P2RX7 (0.60) | LOXL2ULK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537816-B1 | Herbicidal picolinamide derivatives | SHELL INT RESEARCH (NL) | 1996-04-24 | — | — | EP | disclosed |
| US-5371061-A | Herbicidal picolinamide derivatives | AMERICAN CYANAMID COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0537816-A1 | Herbicidal picolinamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-04-21 | — | — | EP | disclosed |