Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977556 | 0.92 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL7974500 | 0.85 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL7977587 | 0.84 | NPC1 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1TDP1 | |
| SCHEMBL7974288 | 0.84 | KMT2A (0.65) | RAB9ASMN1; SMN2NPC1ALDH1A1TDP1 | |
| SCHEMBL1415071 | 0.84 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL1415226 | 0.84 | RAB9A (1.00) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL7964019 | 0.83 | SMN1; SMN2 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL1415002 | 0.82 | RAB9A (0.97) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL7975301 | 0.82 | SMN1; SMN2 (0.48) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL7977633 | 0.81 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |