Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964031 | 0.83 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL7977639 | 0.83 | RAB9A (0.59) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL7963873 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL28693267 | 0.80 | RAB9A (0.54) | SMN1; SMN2RAB9ANPC1KLK7ALDH1A1 | |
| SCHEMBL1415033 | 0.77 | RAB9A (0.78) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL7964060 | 0.75 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL7963947 | 0.75 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL7977556 | 0.74 | SMN1; SMN2 (0.58) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 | |
| SCHEMBL7964029 | 0.73 | RAB9A (0.70) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL7974500 | 0.73 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |