Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415683 | 0.93 | RAB9A (0.42) | RAB9ASMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL7960446 | 0.88 | RAB9A (0.57) | RAB9ASMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL7420636 | 0.81 | SMN1; SMN2 (0.47) | RAB9ASMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL7420722 | 0.77 | MAPT (0.41) | RAB9ASMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL7415629 | 0.77 | TMPRSS4 (0.40) | RAB9ANPC1MAPTPKM | |
| SCHEMBL7959855 | 0.75 | LMNA (0.44) | RAB9ASMN1; SMN2MAPK1KMT2AGAA | |
| SCHEMBL7418952 | 0.75 | RAB9A (0.44) | RAB9ASMN1; SMN2KMT2AGAANPC1 | |
| SCHEMBL7416321 | 0.74 | MAPT (0.47) | RAB9ASMN1; SMN2MAPK1KMT2AGAA | |
| SCHEMBL7411535 | 0.74 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL7964564 | 0.73 | USP2 (0.51) | RAB9ASMN1; SMN2MAPK1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | claimed |
| US-6218384-B1 | FOR THERAPY OF ANXIETY, MUSCLE SPASMS, SLEEPLESSNESS, CONVULSIONS AND BENZODIAZEPINE OVERDOSES | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-04-17 | — | — | US | disclosed |
| US-5639760-A | USEFUL AS MUSCLE RELAXANTS, SEDATIVES, ANXIOLYTICS, ANTICONVULSANTS, AND ANTIDOTES FOR DRUG OVERDOSE | MARYANOFF BRUCE E (US) | 1997-06-17 | — | — | US | disclosed |