Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.45 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962754 | 0.88 | ALDH1A1 (0.56) | MEN1ALDH1A1LMNAKMT2AHRH3 | |
| SCHEMBL7969481 | 0.85 | LTA4H (0.38) | MEN1ALDH1A1LMNAKMT2ADRD3 | |
| SCHEMBL7969477 | 0.85 | MAPT (0.50) | LMNAKMT2A | |
| Oxalic Acid SCHEMBL7966526 | 0.84 | KDM4E (0.54) | MEN1ALDH1A1LMNAKMT2AHRH3 | |
| SCHEMBL7969474 | 0.84 | MAPT (0.38) | MEN1ALDH1A1LMNAKMT2ADRD3 | |
| SCHEMBL7964899 | 0.83 | ALDH1A1 (0.50) | MEN1ALDH1A1LMNAKMT2AHRH3 | |
| SCHEMBL7966189 | 0.83 | LTA4H (0.50) | MEN1ALDH1A1LMNAKMT2AHRH3 | |
| SCHEMBL7966346 | 0.80 | CYP2D6 (0.49) | MEN1ALDH1A1LMNAKMT2AHTR2A | |
| SCHEMBL7965519 | 0.80 | ALDH1A1 (0.51) | MEN1ALDH1A1LMNAKMT2ADRD3 | |
| SCHEMBL7963819 | 0.78 | MAOA (0.46) | LMNADRD3DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |