Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | PPM1G | O15355 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027883 | 0.82 | KDM4E (0.34) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7972438 | 0.77 | ESR2 (0.42) | ESR1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL6026165 | 0.74 | HSD17B1 (0.38) | ESR1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6026481 | 0.69 | MCL1 (0.41) | SMN1; SMN2MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7971494 | 0.69 | ALDH1A1 (0.33) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6926535 | 0.68 | HCAR2 (0.49) | KDM4EMEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL6026628 | 0.68 | MEN1 (0.37) | ALDH1A1MEN1KMT2APOLBLMNA | |
| SCHEMBL6026477 | 0.68 | CHRNA1 (0.39) | KDM4EALDH1A1KMT2ABRD4CYP1A2 | |
| SCHEMBL7984729 | 0.68 | CHRNA1 (0.39) | KDM4EALDH1A1KMT2ABRD4CYP1A2 | |
| SCHEMBL6027636 | 0.67 | ALDH1A1 (0.36) | ESR1KDM4EALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |