Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968549 | 0.84 | MAPT (0.41) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL7969007 | 0.82 | MAPT (0.35) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL6027607 | 0.80 | NQO2 (0.39) | ALDH1A1MAPTTDP1MAPK1MEN1 | |
| SCHEMBL7965276 | 0.74 | HSPB1 (0.40) | ALDH1A1MAPTTDP1MAPK1MEN1 | |
| SCHEMBL7968407 | 0.71 | POLB (0.46) | ALDH1A1MAPTTDP1MAPK1MEN1 | |
| SCHEMBL7968467 | 0.69 | MAPT (0.39) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL7539856 | 0.69 | ABCG2 (0.37) | MAPTMAPK1CA9 | |
| SCHEMBL7965192 | 0.69 | ESR1 (0.40) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL7972386 | 0.67 | MAPT (0.40) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7966269 | 0.67 | LMNA (0.40) | ALDH1A1MAPTSMN1; SMN2ALOX12HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |