Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971994 | 0.82 | PGR (0.37) | ESR2ESR1QPCTHCAR3HCAR2 | |
| SCHEMBL7965192 | 0.77 | ESR1 (0.40) | ESR1MEN1LMNAPOLBMAPT | |
| SCHEMBL6026165 | 0.73 | HSD17B1 (0.38) | ESR2ESR1MEN1LMNAPOLB | |
| SCHEMBL6026477 | 0.70 | CHRNA1 (0.39) | KMT2AHCAR3HCAR2HPGD | |
| SCHEMBL7984729 | 0.70 | CHRNA1 (0.39) | KMT2AHCAR3HCAR2HPGD | |
| SCHEMBL7969007 | 0.69 | MAPT (0.35) | ESR2ESR1MEN1LMNAPOLB | |
| SCHEMBL6026481 | 0.69 | MCL1 (0.41) | MEN1LMNAPOLBMAPTKMT2A | |
| SCHEMBL7965561 | 0.68 | PTGS2 (0.43) | SMN1; SMN2HPGD | |
| SCHEMBL7967042 | 0.68 | PGR (0.36) | ESR2ESR1MEN1LMNAPOLB | |
| SCHEMBL6926535 | 0.67 | HCAR2 (0.49) | MEN1KMT2AHCAR3HCAR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |