Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 3/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898117 | 0.74 | ALDH1A1 (0.43) | CTRCALDH1A1RAB9AHDAC4HDAC2 | |
| SCHEMBL25372606 | 0.73 | LMNA (0.44) | CTRCPTPRCALDH1A1KDM4EMAOB | |
| SCHEMBL8759097 | 0.72 | ALDH1A1 (0.42) | ALDH1A1HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL311581 | 0.72 | CTRC (0.40) | CTRCPTPRCALDH1A1KDM4EMAOB | |
| Ammonia Solution, Strong SCHEMBL27829594 | 0.72 | LMNA (0.43) | CTRCPTPRCALDH1A1KDM4EMAOB | |
| SCHEMBL28190794 | 0.72 | KDM4E (0.48) | CTRCPTPRCALDH1A1KDM4EMAOB | |
| SCHEMBL23925707 | 0.72 | HDAC4 (0.53) | CTRCPTPRCALDH1A1KDM4EMAOB | |
| SCHEMBL7965213 | 0.71 | MAPT (0.39) | CTRCALDH1A1KDM4ERAB9ACA1 | |
| SCHEMBL812897 | 0.69 | CTRC (0.48) | CTRCALDH1A1KDM4EMAOBRAB9A | |
| SCHEMBL828194 | 0.67 | ALDH1A1 (0.37) | ALDH1A1HDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288109-B1 | Pyranones, method for the production and use thereof | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2001-09-11 | — | — | US | disclosed |