Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25372606 | 0.73 | LMNA (0.44) | MAPTHTTLMNAALDH1A1PDGFRA | |
| SCHEMBL27675760 | 0.72 | ALDH1A1 (0.46) | MAPTHTTLMNAALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL27829594 | 0.72 | LMNA (0.43) | MAPTHTTLMNAALDH1A1PDGFRA | |
| SCHEMBL7965216 | 0.71 | CTRC (0.37) | ALDH1A1KMT2ACA1CA9CTRC | |
| SCHEMBL7645357 | 0.69 | MAPT (0.36) | MAPTHTTLMNAALDH1A1POLB | |
| SCHEMBL29109510 | 0.69 | — | — | |
| Ethane SCHEMBL27790626 | 0.69 | ALDH1A1 (0.43) | MAPTHTTLMNAALDH1A1MEN1 | |
| SCHEMBL28166756 | 0.67 | ALDH1A1 (0.37) | MAPTHTTLMNAALDH1A1TSHR | |
| SCHEMBL4067689 | 0.66 | ALDH1A1 (0.40) | MAPTHTTLMNAALDH1A1MAPK1 | |
| SCHEMBL4069489 | 0.66 | ALDH1A1 (0.36) | MAPTHTTLMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288109-B1 | Pyranones, method for the production and use thereof | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2001-09-11 | — | — | US | disclosed |