Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962136 | 0.89 | KCNMA1 (0.35) | KCNMA1DPP4KDM4E | |
| SCHEMBL7961452 | 0.87 | KCNMA1 (0.38) | KCNMA1DPP4KDM4E | |
| SCHEMBL7963738 | 0.86 | KCNMA1 (0.37) | KCNMA1DPP4 | |
| SCHEMBL7967718 | 0.85 | KCNMA1 (0.36) | KCNMA1DPP4 | |
| SCHEMBL7961349 | 0.84 | KCNMA1 (0.34) | KCNMA1DPP4KDM4E | |
| SCHEMBL7952972 | 0.83 | HCRTR1 (0.34) | — | |
| SCHEMBL7961238 | 0.81 | ALDH1A1 (0.32) | — | |
| SCHEMBL7961681 | 0.81 | CYP11B2 (0.37) | KDM4E | |
| SCHEMBL8329371 | 0.80 | DPP4 (0.35) | KCNMA1DPP4KDM4E | |
| SCHEMBL7964348 | 0.79 | KDM4E (0.35) | KCNMA1DPP4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |