Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965342 | 0.84 | KMT2A (0.44) | DRD4 | |
| SCHEMBL7965345 | 0.82 | SLC6A1 (0.34) | OPRL1DRD2DRD4DRD3 | |
| SCHEMBL8132545 | 0.82 | NOTUM (0.33) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL7965447 | 0.80 | HRH3 (0.36) | DRD3 | |
| Succinic Acid SCHEMBL7965776 | 0.80 | ITGA4 (0.34) | OPRM1OPRD1OPRK1OPRL1DRD2 | |
| SCHEMBL7967120 | 0.80 | ABCB1 (0.41) | DRD2DRD3 | |
| SCHEMBL7965737 | 0.79 | HTR1A (0.41) | DRD2DRD4DRD3 | |
| SCHEMBL7963263 | 0.78 | — | — | |
| Malonic Acid SCHEMBL7953257 | 0.78 | TP53 (0.36) | DRD2DRD4DRD3 | |
| SCHEMBL7963097 | 0.77 | HRH3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |