Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968891 | 0.85 | RAB9A (0.40) | GAAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1388445 | 0.70 | CA12 (0.37) | KDM4EGAAHTTALDH1A1MEN1 | |
| SCHEMBL8911562 | 0.70 | POLB (0.40) | KDM4EGAAHTTALDH1A1MAPT | |
| SCHEMBL8909629 | 0.69 | CA12 (0.39) | KDM4EGAAHTTALDH1A1MEN1 | |
| SCHEMBL8910230 | 0.66 | GABRA1 (0.38) | KDM4EGAAALDH1A1KMT2AMAPT | |
| SCHEMBL8910142 | 0.66 | GAA (0.33) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL28328600 | 0.58 | CYP2C19 (0.75) | KDM4EALDH1A1KMT2AMAPTCYP2C9 | |
| SCHEMBL844149 | 0.58 | CYP3A4 (0.49) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16175866 | 0.58 | KDM4E (0.68) | KDM4EGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4444431 | 0.58 | CA1 (0.70) | GAAHTTMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201129-B1 | ANTICARCINOGENIC AGENTS | UNIV. COLLEGE CARDIFF CONSULTANTS (GB) | 2001-03-13 | — | — | US | disclosed |