Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950440 | 0.90 | GRM2 (0.36) | CES2CES1APPPSEN1PSEN2 | |
| SCHEMBL4068539 | 0.87 | CES2 (0.41) | CES2CES1ERN1HCAR1SRC | |
| SCHEMBL5255790 | 0.74 | CES2 (0.43) | CES2CES1SRC | |
| SCHEMBL6029780 | 0.74 | HTT (0.41) | — | |
| SCHEMBL8525339 | 0.72 | AKR1C4 (0.45) | ERN1HCAR1SRC | |
| SCHEMBL16460187 | 0.71 | RORC (0.43) | CES2CES1ERN1KEAP1NFE2L2 | |
| SCHEMBL23139047 | 0.70 | MAPK14 (0.31) | — | |
| SCHEMBL6452270 | 0.69 | CES2 (0.53) | CES2CES1ERN1HCAR1SRC | |
| SCHEMBL6306274 | 0.68 | TPMT (0.39) | NOTUMHCAR1SRC | |
| SCHEMBL16996749 | 0.68 | CES2 (0.40) | CES2CES1ERN1HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242451-B1 | Fungicidal trihalophenyl-triazolopyrimidines | BASF AKTIENGESELLSCHAFT | 2001-06-05 | — | — | US | disclosed |