SCHEMBL7965975

SCHEMBL7965975

COCCOCOc1cc(C(Cl)C(=O)O)c(F)c(F)c1OCOCCOC

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RARG P13631 10/20 0.34
F2 P00734 1/20 0.33
ELANE P08246 1/20 0.33
RARA P10276 2/20 0.33
RARB P10826 1/20 0.33
IKBKB O14920 4/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CTNNB1 P35222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7961386 0.82 F2 (0.37) RARGF2ELANERARARARB
SCHEMBL7964642 0.79 F2 (0.41) RARGF2ELANERARARARB
SCHEMBL7962141 0.75 BLM (0.37) RARGF2ELANERARARARB
SCHEMBL8747650 0.74 F2 (0.39) RARGF2ELANERARARARB
SCHEMBL7964173 0.74 RARA (0.38) RARGF2ELANERARARARB
SCHEMBL7964175 0.74 RARA (0.38) RARGF2ELANERARARARB
SCHEMBL7961925 0.72 ALDH1A1 (0.33) RARGF2ELANERARAIKBKB
SCHEMBL7962067 0.71 RARG (0.40) RARGF2ELANERARARARB
SCHEMBL7960031 0.71 RARG (0.33) RARGF2ELANERARARARB
SCHEMBL7951445 0.70 THRB (0.43) RARGF2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313305-B1 ANTIBIOTICS, BACTERICIDES HOECHST MARION ROUSSEL (FR) 2001-11-06 US disclosed
US-5587372-A BACERICIDES ROUSSEL UCLAF (FR) 1996-12-24 US disclosed