Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140203 | 0.86 | MAT2A (0.44) | HRH4MEN1KMT2AMAT2ANPC1 | |
| SCHEMBL7976237 | 0.82 | SMN1; SMN2 (0.38) | HRH4MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL10133974 | 0.66 | SIGMAR1 (0.58) | MEN1KMT2ANPC1SMN1; SMN2RAB9A | |
| SCHEMBL13227195 | 0.65 | MAPK1 (0.48) | HRH4MEN1KMT2AMAT2AMAPT | |
| SCHEMBL31577611 | 0.65 | KDM4E (0.60) | HRH4MEN1KMT2AMAT2ANPC1 | |
| SCHEMBL19353933 | 0.65 | HRH4 (0.45) | HRH4MEN1KMT2AMAT2ARAB9A | |
| SCHEMBL19353934 | 0.64 | HRH4 (0.43) | HRH4MEN1KMT2AMAT2ARAB9A | |
| SCHEMBL7970287 | 0.64 | AMY1A (0.46) | HRH4MEN1KMT2AMAT2ARAB9A | |
| SCHEMBL28087556 | 0.64 | HTT (0.52) | HRH4SMN1; SMN2MAPT | |
| SCHEMBL28087640 | 0.63 | RXFP1 (0.53) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |