Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493966 | 0.87 | KMT2A (0.36) | KMT2APKMMAPTCHRNB2CHRNB4 | |
| SCHEMBL7493957 | 0.87 | KMT2A (0.36) | KMT2APKMMAPTCHRNB2CHRNB4 | |
| SCHEMBL7499837 | 0.87 | KMT2A (0.36) | KMT2APKMMAPTCHRNB2CHRNB4 | |
| SCHEMBL7500612 | 0.84 | HTT (0.34) | KMT2ACCR8CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7497433 | 0.83 | KMT2A (0.35) | KMT2APKMMAPTCCR8CHRNB2 | |
| SCHEMBL7496325 | 0.79 | CACNA2D1 (0.41) | KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7491286 | 0.79 | ALDH1A1 (0.40) | TSHR | |
| SCHEMBL7528853 | 0.78 | POLB (0.43) | KMT2AMAPTCCR8CHRNB2CHRNB4 | |
| SCHEMBL7505927 | 0.77 | SLC6A2 (0.36) | GPR119CHRNB2CHRNA4TSHRCYP2D6 | |
| SCHEMBL6499006 | 0.77 | EPHX2 (0.36) | KMT2ACPN1CPB2SSTR4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068604-A2 | 3-SUBSTITUTED PIPERIDINES COMPRISING UREA FUNCTIONALITY, AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2001-09-20 | — | — | WO | disclosed |