SCHEMBL7967372

SCHEMBL7967372

Fc1[c]ccc(C(F)(F)F)c1-c1ccc(C(F)(F)F)c(F)c1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 12/20 0.49
CYP11B2 P19099 8/20 0.42
CYP11B1 P15538 6/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8079532 0.77 AR (0.33) KIF11
SCHEMBL21116892 0.75 KIF11 (0.76) KIF11CYP11B2CYP11B1
SCHEMBL3895116 0.70 KIF11 (0.68) KIF11CYP11B2CYP11B1
SCHEMBL8015228 0.70 CYP11B2 (0.57) KIF11CYP11B2CYP11B1
SCHEMBL7981007 0.70 KMO (0.40) CYP11B2CYP11B1
SCHEMBL3121614 0.70 KIF11 (0.45) KIF11CYP11B2CYP11B1
SCHEMBL144187 0.68 IDO1 (0.32)
SCHEMBL6120541 0.67 KIF11 (0.69) KIF11CYP11B2CYP11B1
SCHEMBL1445741 0.66
SCHEMBL3903111 0.66 KIF11 (0.72) KIF11CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001092236-A1 4-ALKYL HALIDE TRIAZINE COMPOUNDS USED AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-12-06 WO disclosed