Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064206 | 0.82 | ESR1 (0.31) | — | |
| SCHEMBL8074556 | 0.79 | HTR2A (0.32) | — | |
| SCHEMBL7967372 | 0.77 | KIF11 (0.49) | KIF11 | |
| SCHEMBL8079925 | 0.77 | HSD17B1 (0.33) | — | |
| SCHEMBL8074574 | 0.73 | RXRA (0.33) | AR | |
| SCHEMBL8072388 | 0.72 | AR (0.33) | ARNR1H2NR1H3 | |
| SCHEMBL8074688 | 0.72 | ESR1 (0.31) | — | |
| SCHEMBL8074381 | 0.71 | RXRA (0.34) | KIF11 | |
| SCHEMBL8066042 | 0.70 | HSD17B1 (0.33) | — | |
| SCHEMBL8066038 | 0.70 | ALOX5AP (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |