SCHEMBL7981007

SCHEMBL7981007

FC(F)(F)c1ccc(-c2c(Cl)[c]ccc2C(F)(F)F)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMO O15229 2/20 0.40
DAO P14920 1/20 0.34
NOTUM Q6P988 7/20 0.33
SCN9A Q15858 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
CYP1A2 P05177 1/20 0.33
FAAH O00519 3/20 0.32
GRM2 Q14416 1/20 0.32
TRPV3 Q8NET8 1/20 0.32
AR P10275 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7615380 0.72 CYP11B1 (0.31) CYP11B1CYP11B2
SCHEMBL19744126 0.71 PDE3B (0.31) NOTUMCYP1A2
SCHEMBL1966360 0.70 P2RX7 (0.36) NOTUM
SCHEMBL7967372 0.70 KIF11 (0.49) CYP11B1CYP11B2
SCHEMBL1274798 0.70 HSD11B1 (0.42) KMOCYP1A2GRM2
SCHEMBL1041026 0.69 ESR2 (0.52) KMOCYP1A2FAAHARCYP11B2
SCHEMBL7281497 0.67 AHR (0.52) KMONOTUM
SCHEMBL7803250 0.67 KIF11 (0.41) NOTUM
SCHEMBL15090399 0.67 KIF11 (0.49) KMODAONOTUMFAAHTRPV3
SCHEMBL7699908 0.66 AHR (0.45) NOTUMAKR1C3AKR1C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001092236-A1 4-ALKYL HALIDE TRIAZINE COMPOUNDS USED AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-12-06 WO disclosed