Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304740 | 0.87 | PTGS2 (0.50) | PTGS2ALDH1A1TSHRTDP1KDM4E | |
| SCHEMBL8986261 | 0.84 | KDM4E (0.38) | ALDH1A1KDM4EPKMCA2HSD17B10 | |
| SCHEMBL8986287 | 0.82 | KDM4E (0.40) | ALDH1A1TSHRKDM4EPKMCA2 | |
| SCHEMBL1530698 | 0.82 | HSD17B10 (0.47) | PTGS2ALDH1A1TSHRTDP1CA2 | |
| Methoxymethane SCHEMBL8986260 | 0.81 | KDM4E (0.39) | ALDH1A1TSHRKDM4EPKMCA2 | |
| SCHEMBL17291956 | 0.80 | PTGDR2 (0.35) | PTGS2ALDH1A1KDM4EADRA2AADRA2C | |
| SCHEMBL363341 | 0.80 | KDM4E (0.45) | ALDH1A1KDM4EPKMCA2HSD17B10 | |
| SCHEMBL14112766 | 0.80 | ALOX15 (0.44) | PTGS2ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL13688744 | 0.79 | ALDH1A1 (0.42) | PTGS2ALDH1A1TSHRTDP1ADRA2A | |
| SCHEMBL14594236 | 0.79 | ALDH1A1 (0.46) | PTGS2ALDH1A1TSHRTDP1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3260461-B1 | PHOSPHITE COMPOUND, METHOD FOR PRODUCING THE SAME AND USES THEREOF | SUMITOMO CHEMICAL CO (JP) | 2019-10-16 | — | — | EP | disclosed |
| US-9902747-B2 | Phosphite compound, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-27 | — | — | US | disclosed |
| US-9902747-B2 | Phosphite compound, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-02-27 | — | — | US | disclosed |
| US-20180002359-A1 | PHOSPHITE COMPOUND, METHOD FOR PRODUCING THE SAME AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-04 | — | — | US | disclosed |
| EP-3260461-A1 | PHOSPHITE COMPOUND, METHOD FOR PRODUCING THE SAME AND USES THEREOF | Sumitomo Chemical Company, Ltd. (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-6251928-B1 | ADMINISTERING BENZYLIDENE RHODANINES WHICH ARE USEFUL AS AGENTS IN TREATING OR PREVENTING CONDITIONS ASSOCIATED WITH BETA-AMYLOID PEPTIDE IN A MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002359-A1 | PHOSPHITE COMPOUND, METHOD FOR PRODUCING THE SAME AND USES THEREOF | PHOSPHO1, AGPS, PLCG1 | PTGS2 2880/4885ALDH1A1 3839/4885TSHR 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.