Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968046 | 0.84 | PTGS2 (0.41) | KDM4EPKMHSD17B10CA2CA4 | |
| SCHEMBL8986287 | 0.82 | KDM4E (0.40) | KDM4EPKMHSD17B10CA2CA4 | |
| Methoxymethane SCHEMBL8986260 | 0.81 | KDM4E (0.39) | KDM4EPKMHSD17B10CA2CA4 | |
| SCHEMBL363341 | 0.80 | KDM4E (0.45) | KDM4EPKMHSD17B10CA2CA4 | |
| Hydrochloric Acid SCHEMBL28586799 | 0.78 | KDM4E (0.44) | KDM4EPKMHSD17B10CA2CA4 | |
| SCHEMBL4735982 | 0.78 | KDM4E (0.44) | KDM4EPKMHSD17B10CA2CA4 | |
| SCHEMBL18560456 | 0.74 | KDM4E (0.44) | KDM4EPKMHSD17B10MAPTHTT | |
| SCHEMBL11216824 | 0.74 | HSD17B10 (0.52) | KDM4EPKMHSD17B10CA2CA4 | |
| SCHEMBL11933625 | 0.72 | ACHE (0.50) | KDM4EPKMCA2CA4MAPT | |
| SCHEMBL14394921 | 0.72 | KDM4E (0.41) | KDM4EPKMHSD17B10CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486559-A | CHARGE TRANSFER ABSORPTION BAND FOR DOPANTS | AKZO NOBEL NV (NL) | 1996-01-23 | — | — | US | disclosed |
| EP-0639786-A1 | Optically non-linear active waveguiding material comprising donor and acceptor groups-containing triphenylcarbinols | Akzo Nobel N.V. (NL) | 1995-02-22 | — | — | EP | disclosed |