Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328923 | 0.91 | DHODH (0.37) | FAAHHCRTR1HCRTR2ALDH1A1CYP2C19 | |
| SCHEMBL7961656 | 0.91 | FAAH (0.34) | FAAHHCRTR1HCRTR2SCN9AALDH1A1 | |
| SCHEMBL7962570 | 0.90 | CDK5 (0.34) | FAAHHCRTR2ALDH1A1CYP2C19AVPR2 | |
| SCHEMBL7963165 | 0.88 | SCN9A (0.34) | HCRTR1HCRTR2SCN9AALDH1A1ZAP70 | |
| SCHEMBL7961792 | 0.87 | DHODH (0.36) | FAAHHCRTR1HCRTR2ALDH1A1CYP2C19 | |
| SCHEMBL7952522 | 0.87 | ALDH1A1 (0.35) | FAAHHCRTR1HCRTR2ALDH1A1CYP2C19 | |
| SCHEMBL7964348 | 0.82 | KDM4E (0.35) | ALDH1A1HPGD | |
| SCHEMBL7961238 | 0.82 | ALDH1A1 (0.32) | HCRTR1HCRTR2ALDH1A1CYP2C19HPGD | |
| SCHEMBL7962103 | 0.82 | MEN1 (0.35) | ALDH1A1CYP2C19HPGDCDK5DYRK1A | |
| SCHEMBL7961108 | 0.81 | DHODH (0.35) | HCRTR1HCRTR2ALDH1A1CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | claimed |
| EP-0946555-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1999-10-06 | — | — | EP | claimed |
| WO-1998025925-A1 | PYRROLE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1998-06-18 | — | — | WO | claimed |
| US-6207675-B1 | FOR PROPHYLAXIS AND THERAPY OF DISEASES IN WHICH ARE INVOLVED VIRUSES OF THE HERPES FAMILY AND/OR CYTOKINES IN PARTICULAR TUMOR NERCOSIS FACTOR-ALPHA | RHONE-POULENC RORER S.A. (FR) | 2001-03-27 | — | — | US | disclosed |