Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7539856 | 0.81 | ABCG2 (0.37) | MAPTCA1CA2CA9RAB9A | |
| SCHEMBL6026229 | 0.79 | ADK (0.39) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL7971836 | 0.78 | APP (0.49) | MAPTMEN1KMT2ACA12CA9 | |
| SCHEMBL7966269 | 0.77 | LMNA (0.40) | MAPTLMNAHTTCA12CA9 | |
| SCHEMBL14071658 | 0.76 | LOXL2 (0.55) | MAPTMEN1KMT2ANPBWR1LMNA | |
| SCHEMBL6932932 | 0.75 | MDM2 (0.38) | MAPTKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6932670 | 0.74 | MDM2 (0.38) | MAPTMEN1KMT2AHTTNPC1 | |
| SCHEMBL6932601 | 0.72 | CFTR (0.43) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL128402 | 0.71 | LOXL2 (0.61) | MAPTMEN1KMT2ANPBWR1ALDH1A1 | |
| SCHEMBL6026268 | 0.70 | CFTR (0.39) | MAPTMEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |