Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932932 | 0.90 | MDM2 (0.38) | ACHEHSD17B10MMP2MMP9MMP8 | |
| SCHEMBL7956300 | 0.85 | LMNA (0.43) | LMNASMN1; SMN2HSD17B10MAPTNPSR1 | |
| SCHEMBL6932670 | 0.81 | MDM2 (0.38) | SMN1; SMN2HTTMAPTPOLBMDM2 | |
| SCHEMBL7968407 | 0.79 | POLB (0.46) | LMNASMN1; SMN2HTTMMP2MMP9 | |
| SCHEMBL7972386 | 0.77 | MAPT (0.40) | LMNASMN1; SMN2ACHEHSD17B10MMP2 | |
| SCHEMBL7968467 | 0.77 | MAPT (0.39) | LMNAHTTMAPTPOLBALDH1A1 | |
| SCHEMBL7971858 | 0.75 | MCL1 (0.38) | LMNAMAPTNPSR1POLBALOX12 | |
| SCHEMBL7586371 | 0.74 | AKR1C2 (0.41) | LMNASMN1; SMN2MAPTNPSR1POLB | |
| SCHEMBL7539856 | 0.74 | ABCG2 (0.37) | MAPTPOLBRAB9ACA9 | |
| SCHEMBL6934449 | 0.74 | AKR1C2 (0.41) | LMNASMN1; SMN2MAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |