Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TNKS | O95271 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967042 | 0.86 | PGR (0.36) | APPMAPTALDH1A1POLBRAB9A | |
| SCHEMBL7969007 | 0.85 | MAPT (0.35) | APPMAPTALDH1A1POLBCTDSP1 | |
| SCHEMBL7968407 | 0.81 | POLB (0.46) | APPMAPTALDH1A1POLBRAB9A | |
| SCHEMBL7965276 | 0.79 | HSPB1 (0.40) | APPMAPTALDH1A1POLBCTDSP1 | |
| SCHEMBL7968549 | 0.79 | MAPT (0.41) | MAPTALDH1A1POLBRAB9AAR | |
| SCHEMBL7971994 | 0.78 | PGR (0.37) | APP | |
| SCHEMBL7972386 | 0.78 | MAPT (0.40) | MAPTALDH1A1POLBRAB9AKMT2A | |
| SCHEMBL7968467 | 0.78 | MAPT (0.39) | MAPTALDH1A1POLBRAB9ACA12 | |
| SCHEMBL7539856 | 0.76 | ABCG2 (0.37) | MAPTPOLBRAB9ACA9 | |
| SCHEMBL7966269 | 0.74 | LMNA (0.40) | MAPTALDH1A1POLBRAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |