Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11562263 | 0.85 | ACHE (0.54) | ACHEHTR1AHTR7CCR5DRD2 | |
| SCHEMBL11567764 | 0.84 | HTR1A (0.54) | ACHEHTR1AHTR7CCR5DRD2 | |
| SCHEMBL8460693 | 0.83 | ACHE (0.65) | ACHEHTR1AHTR7CCR5DRD2 | |
| SCHEMBL11567913 | 0.82 | ACHE (0.57) | ACHEHTR1AHTR7CCR5DRD2 | |
| SCHEMBL7978877 | 0.78 | DRD2 (0.55) | ACHEHTR1AHTR7POLBCCR5 | |
| Hydrochloric Acid SCHEMBL7969030 | 0.78 | ACHE (0.46) | ACHEHTR1AHTR7POLBTHRB | |
| Hydrochloric Acid SCHEMBL7978864 | 0.77 | CCR5 (0.47) | ACHEHTR1AHTR7CCR5DRD2 | |
| SCHEMBL11563843 | 0.77 | DRD2 (0.46) | ACHEHTR7CCR5DRD2SLC6A4 | |
| SCHEMBL30169432 | 0.76 | ACVR1 (0.51) | ACHECCR5DRD2SLC6A4ACVR1 | |
| SCHEMBL7981807 | 0.76 | ACHE (0.45) | ACHEHTR1AHTR7POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |