Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973958 | 0.89 | LMNA (0.38) | BRS3KMT2A | |
| SCHEMBL7970889 | 0.77 | TAAR1 (0.47) | — | |
| SCHEMBL7969211 | 0.67 | CPA1 (0.42) | BRS3KDM4EALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL7969213 | 0.66 | FABP4 (0.37) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7971080 | 0.66 | TAAR1 (0.47) | — | |
| SCHEMBL10503730 | 0.63 | MAPK1 (0.42) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9450042 | 0.63 | KDM4E (0.56) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6880258 | 0.62 | KMT2A (0.52) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL729589 | 0.61 | ALDH1A1 (0.57) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10505059 | 0.61 | USP2 (0.44) | KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009127-A1 | BENZOXAZINE DERIVATIVES AND THEIR THERAPEUTIC USE | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |