Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969643 | 0.80 | NFE2L2 (0.38) | NPC1RAB9ACYP11B2ALDH1A1MAPT | |
| SCHEMBL7971462 | 0.77 | NFE2L2 (0.39) | NPC1RAB9AMAPTGAATDP1 | |
| SCHEMBL7969857 | 0.75 | NFE2L2 (0.49) | KMT2AMEN1MAPTSMN1; SMN2GRM5 | |
| SCHEMBL8911420 | 0.74 | ALDH1A1 (0.62) | NPC1RAB9AKMT2AMEN1CYP11B2 | |
| SCHEMBL11180576 | 0.73 | NPC1 (0.73) | NPC1RAB9AKMT2AMEN1CYP11B2 | |
| SCHEMBL7970291 | 0.72 | TP53 (0.44) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL8435518 | 0.71 | CYP1A1 (0.54) | CYP11B2ALDH1A1CYP11B1MAPTSMN1; SMN2 | |
| SCHEMBL27515192 | 0.71 | MAPT (0.54) | NPC1RAB9ACYP11B2ALDH1A1CYP11B1 | |
| SCHEMBL7972007 | 0.69 | NFE2L2 (0.54) | NPC1RAB9AKMT2AMEN1CYP19A1 | |
| SCHEMBL3142532 | 0.69 | CYP11B2 (0.68) | NPC1RAB9AKMT2AMEN1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |