Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961051 | 0.86 | ALDH1A1 (0.37) | ALDH1A1APEX1IMPDH1LMNAMEN1 | |
| SCHEMBL7971104 | 0.81 | APEX1 (0.36) | APEX1LMNATDP1PDE3A | |
| SCHEMBL7974408 | 0.79 | EPHX2 (0.39) | ALDH1A1LMNAHDAC11FABP4MEN1 | |
| SCHEMBL7974482 | 0.77 | ALDH1A1 (0.39) | ALDH1A1IMPDH1TSHRLMNANFKB1 | |
| SCHEMBL7974475 | 0.73 | CYP4F2 (0.43) | APEX1LMNATDP1PDE3A | |
| SCHEMBL7974447 | 0.72 | CYP4F2 (0.43) | ALDH1A1LMNATDP1MEN1KMT2A | |
| SCHEMBL5070469 | 0.72 | HDAC3 (0.46) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL1100247 | 0.71 | LMNA (0.41) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL250989 | 0.69 | TSHR (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 | |
| SCHEMBL250466 | 0.69 | TSHR (0.52) | ALDH1A1TSHRLMNANFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |