Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30519457 | 0.94 | MAPT (0.42) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL1144804 | 0.94 | MAPT (0.42) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL4101620 | 0.86 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL5349206 | 0.86 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL1144675 | 0.85 | SMN1; SMN2 (0.44) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL13846009 | 0.85 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL22005000 | 0.84 | MAPT (0.50) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL5316970 | 0.81 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL2974587 | 0.80 | MAPT (0.56) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL21169162 | 0.79 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2015-05-14 | — | — | US | disclosed |
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2015-05-14 | — | — | US | disclosed |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2012-03-22 | — | — | US | disclosed |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | PHOTOBIOTICS LIMITED (GB) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133653-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | L3MBTL1 1047/4885ALDH1A1 371/4885LMNA 1929/4885 |
| US-20120070377-A1 | COMPOUNDS AND BIOLOGICAL MATERIALS AND USES THEREOF | SSB, HLA-B, BDKRB1 | L3MBTL1 1552/4885ALDH1A1 278/4885LMNA 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.