Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD5 | P21918 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983420 | 0.96 | HTR1A (0.55) | HTR1ASIGMAR1KCNH2DRD3DRD2 | |
| SCHEMBL7986389 | 0.86 | CCR3 (0.50) | SIGMAR1 | |
| SCHEMBL8828516 | 0.84 | DRD2 (0.51) | HTR1ADRD3DRD2HTR7 | |
| SCHEMBL7986525 | 0.82 | CCR3 (0.56) | — | |
| SCHEMBL7989675 | 0.81 | SIGMAR1 (0.54) | SIGMAR1DRD2HTR7PARP1CYP2D6 | |
| SCHEMBL23142609 | 0.81 | CCNE2 (0.43) | SIGMAR1 | |
| SCHEMBL4910767 | 0.81 | CHEK1 (0.50) | HTR1ASIGMAR1DRD2PARP1 | |
| SCHEMBL8557009 | 0.80 | CHEK1 (0.47) | SIGMAR1PARP1 | |
| SCHEMBL3174237 | 0.80 | CHEK1 (0.47) | SIGMAR1DRD3DRD2PARP1 | |
| SCHEMBL7971599 | 0.80 | CCR3 (0.54) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |